Anti-GFAP Recombinant Chicken Chimeric mAb FL550 Conjugate (N206A/8)

Name: Anti-GFAP Recombinant Chicken Chimeric mAb FL550 Conjugate
Brand: Aves Labs
SKU: 78-240-FL550
Price: 549.0 USD
Availability: InStock

Our chicken Anti-GFAP recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N206A/8. It is KO validated, detects drosophila, guinea pig, human, mouse, polar bear, and rat GFAP, and is purified by affinity chromatography. It is great for use in ICC, IHC, WB.

Anti-GFAP Recombinant Chicken Chimeric mAb FL550 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

594

650

Carrier-Free

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Data Sheet

KO Validated

SKU: 78-240-FL550

Volume: 200 µL

Variant

Price:

$549.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GFAP

Scientific Background

Glial fibrillary acidic protein (GFAP) is an intermediate filament with many different isoforms, and acts as a structural protein in the cytoskeleton. It is expressed in astrocytes in brain and is often used as an astrocyte marker. GFAP is believed to be involved in many CNS processes including cell communication and mitosis. GFAP has been found to be involved in Alexander disease and Wernicke's encephalopathy.

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

N206A/8

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

GFAP

Molecular Weight

50 kDa

Excitation / Emission

FL550 Ex: 550 nm, Em: 575 nm

Immunogen

Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136)

Immunogen Species

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of our NeuroMab clone N206A/8 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N206A/8 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

550

Specificity

Cross-reacts with GFAP-R416W and other GFAP mutant proteins. Does not cross-react with other proteins (based on KO validation results).

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Glial fibrillary acidic protein (GFAP)

UniProt ID

P14136

Shipping

Shipped on ice packs

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Anti-GFAP Recombinant Chicken Chimeric mAb FL550 Conjugate (N206A/8)

SKU: 78-240-FL550

Product Details

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