Anti-Calretinin Recombinant Chicken Chimeric mAb FL490 Conjugate (L122/6)

Name: Anti-Calretinin Recombinant Chicken Chimeric mAb FL490 Conjugate
Brand: Aves Labs
SKU: 78-488-FL490
Price: 549.0 USD
Availability: InStock

Our chicken Anti-Calretinin recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone L122/6. It detects human, mouse, and rat Calretinin, and is purified by affinity chromatography. It is great for use in ICC, IHC, WB.

Anti-Calretinin Recombinant Chicken Chimeric mAb FL490 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

550

594

650

Carrier-Free

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Data Sheet

SKU: 78-488-FL490

Volume: 200 µL

Variant

Price:

$549.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Calretinin

Scientific Background

Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

L122/6

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

CALB2 CAB29

Molecular Weight

25-35 kDa

Excitation / Emission

FL490 Ex: 491 nm, Em: 515 nm

Immunogen

Fusion protein amino acids 1-178 (N-terminus) of human CALB2 (accession number) produced recombinantly in E. Coli

Immunogen Species

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of our NeuroMab clone L122/6 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone L122/6 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

490

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

CALB2 (Calretinin) (29 kDa calbindin)

UniProt ID

P22676

Shipping

Shipped on ice packs

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Anti-Calretinin Recombinant Chicken Chimeric mAb FL490 Conjugate (L122/6)

SKU: 78-488-FL490

Product Details

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