Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody (4)

Name: Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody
Brand: Antibodies Incorporated
SKU: ABS 051-04-010
Price: 450.0 USD
Availability: InStock

Our mouse PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 4. It detects human PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) and is Protein A or Protein G purified. Works in ELISA, WB.

Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody

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Species Reactivity

Human

Applications

ELISA, WB

Host Species

Mouse

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Data Sheet

SKU: ABS 051-04-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36)

Scientific Background

Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

Isotype

IgG2a/k

Applications

ELISA, WB

Host Species

Mouse

Gene Name

PYY

Molecular Weight

4 kDa

Immunogen

Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.

Immunogen Species

Human

Species Reactivity

Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Dilution Ranges

ELISA: 1:20,000

Application Details

ABS 051-04 binds free PYY(3-36) in solution. An ELISA dilution guideline of 1/20,000 applies to PYY(3-36) coated directly at 1 μg/mL. ABS 051-04 as a capture antibody forms a sandwich ELISA antibody pair with biotinylated ABS 029-01 as a detection antibody for measuring PYY(3-36).

Conjugate

Unconjugated

Specificity

ABS 051-04 binds human PYY(3-36). Based on inhibition ELISA, ABS 051-04 shows no cross-reaction with PYY(1-36) or NPY. The epitope lies within residues 3-12 of human PYY.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY

UniProt ID

P10082

NCBI Gene ID

5697

Shipping

Shipped on ice packs

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Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody (4)

SKU: ABS 051-04-010

Product Details

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