Anti-Pink1 PTEN Induced Putative Kinase 1 Recombinant Chicken Chimeric mAb FL594 Conjugate (N4/15)

Name: Anti-Pink1 PTEN Induced Putative Kinase 1 Recombinant Chicken Chimeric mAb FL594 Conjugate
Brand: Aves Labs
SKU: 78-060-FL594
Price: 562.0 USD
Availability: InStock

Our chicken Anti-Pink1 PTEN induced putative kinase 1 FL594 conjugate recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone N4/15. It detects human, mouse, and rat Pink1 PTEN induced putative kinase 1 and is purified by affinity chromatography. Works in IHC, ICC.

Anti-Pink1 PTEN Induced Putative Kinase 1 Recombinant Chicken Chimeric mAb FL594 Conjugate

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Applications

ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

550

650

Biotin

Carrier-Free

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Data Sheet

SKU: 78-060-FL594

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Pink1 PTEN induced putative kinase 1

Scientific Background

PTEN Induced Kinase 1 is encoded by the gene PINK1. PINK1 is a member of the protein kinase superfamily, Ser/Thr protein kinase family. PINK1 is a serine/threonine protein kinase that protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. PINK1 is highly expressed in the heart, skeletal muscle, and testis. Diseases associated with PINK1 include Parkinson Disease 6, Autosomal Recessive Early-Onset and Parkinson Disease 2, Autosomal Recessive Juvenile.

Format

Purified by affinity chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Recombinant

Clone

N4/15

Isotype

IgY

Applications

ICC, IHC

Host Species

Chicken

Gene Name

PINK1

Molecular Weight

63 kDa

Excitation / Emission

FL594 Ex: 594 nm, Em: 615 nm

Immunogen

Fusion protein amino acids 112-496 of human Pink1 (accession number NP_115785) produced recombinantly in E. Coli

Immunogen Species

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone N4/15 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N4/15 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Dilution Ranges

IHC: 1:200-1:1000
ICC: 1:200-1:1000

Conjugate

594

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)

UniProt ID

Q9BXM7

Shipping

Shipped on ice packs

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Anti-Pink1 PTEN Induced Putative Kinase 1 Recombinant Chicken Chimeric mAb FL594 Conjugate (N4/15)

SKU: 78-060-FL594

Product Details

Bulk Order Anti-Pink1 PTEN Induced Putative Kinase 1 Recombinant Chicken Chimeric mAb FL594 Conjugate

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