Anti-Peptide YY Antibody (1)
Our mouse Peptide YY monoclonal antibody from Antibodies Incorporated is produced in-house from clone 1. It detects human Peptide YY and is Protein A or Protein G purified. Works in ELISA, IHC.
Immunohistochemistry detection of Peptide YY in human small intestine tissue using Anti-Peptide YY Antibody (Cat. ABS 029-01-010). Tissue was mounted and pariffin fixed. Heat induced antigen retrieval was performed using citrate buffer, heated, and then blocked. After washing, the primary antibody (Cat. ABS 029-01-010) was incubated with the sample.
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SKU: ABS 029-01-010
Ships: 1-2 business days
Product Details
Peptide YY
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
1
IgG1/k
ELISA, IHC
Mouse
PYY
10 kDa (preproprotein), 5 kDa (mature pepide)
Synthetic human PYY
Human
Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
ABS 029-01 binds free PYY in solution. ABS 029-01 reacts in ELISA with PYY coated directly onto the microtiter well. Biotinylated ABS 029-01 can be used as a detection antibody with ABS 051-04 as a capture antibody for measuring PYY(3-36) by sandwich ELISA.
Unconjugated
ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1%.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY
5697
Shipped on ice packs

