Anti-PARIS/ZNF746 Antibody (N196/16)

Name: Anti-PARIS/ZNF746 Antibody
Brand: NeuroMab
SKU: 75-195
Price: 337.0 USD
Availability: InStock

Our mouse PARIS/ZNF746 monoclonal antibody from NeuroMab is produced in-house from clone N196/16. It detects drosophila, human, mouse, non-human primate, and rat PARIS/ZNF746 and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged ZNF746, V5-tagged ZNF398, V5-tagged ZNF783 or untagged Kv2.1 plasmid and probed with N196/16 TC supe (left), N86/8 TC supe (middle) or Rabbit anti-V5.

Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with N196/16 (left) or N52A/42 (right) TC supe.

Adult rat brain immunohistochemistry.

Click on image to zoom

Species Reactivity

Drosphila, Human, Mouse, Non-Human Primate, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-195

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

PARIS/ZNF746

Scientific Background

Zinc finger protein 746, Parkin-Interacting Substrate or PARIS/ZNF746 is encoded by the gene ZNF746. PARIS is a transcription repressor that binds to a consensus sequence on promoters and represses the expression of a transcriptional coactivator, PGC-1-alpha (PPARGC1A). This protein plays a role in regulation of neuron death. PARIS is found in the cytoplasm and nucleus

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N196/16

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

ZNF746 PARIS

Molecular Weight

60-70 kDa

Immunogen

Fusion protein amino acids 1-322 (N-terminus) of human ZNF746 (accession number Q6NUN9) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Drosphila, Human, Mouse, Non-Human Primate, Rat

Antibody Registry ID

AB_10674714

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.123

Conjugate

Unconjugated

Specificity

Does not cross-react with ZNF783 or ZNF398

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Zinc finger protein 746 (Parkin-interacting substrate) (PARIS)

UniProt ID

Q6NUN9

Shipping

Shipped on ice packs

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Anti-PARIS/ZNF746 Antibody (N196/16)

SKU: 75-195

Product Details

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