Anti-Pan-KChIP K+ Channel Antibody (K55/82)

Name: Anti-Pan-KChIP K+ Channel Antibody
Brand: NeuroMab
SKU: 75-006
Price: 337.0 USD
Availability: InStock

Our mouse Pan-KChIP K+ channel monoclonal antibody from NeuroMab is produced in-house from clone K55/82. It detects human, mouse, and rat Pan-KChIP K+ channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat hippocampus immunohistochemistry.

Immunoblot versus crude brain membranes from adult mouse (MBM), rat (RBM) and human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] and cerebellum [HBM(Cb)] probed with K55/82 (left) and N52A/42 (right) TC supe.

Adult rat hippocampus immunohistochemistry.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-006

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Pan-KChIP K+ channel

Scientific Background

The Kv channel-interacting proteins (KChIP1, kChIp2, kChIp3, and kChIp4) are members of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. They serve as auxiliary channel subunits and interact with Kv4 alpha subunits to form native Kv4 channel complexes. KChiP subunits regulate Kv4 channels through various mechanisms including altering: channel density, inactivation kinetics, rate of recovery from inactivation, and cell surface delivery.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K55/82

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnip1 Kchip1

Molecular Weight

33 kDa (KChIP2), 25 kDa (KChIP3/4), 22 kDa (KChIP1)

Immunogen

Fusion protein amino acids 1-227 (full length) of rat KChIP1b (accession number Q8R426) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10673406

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Dilution Ranges

WB: 1:1000
IHC: 1:250
ICC: 1:250

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1)

UniProt ID

Q8R426

Shipping

Shipped on ice packs

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Anti-Pan-KChIP K+ Channel Antibody (K55/82)

SKU: 75-006

Product Details

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