Anti-nNOS/NOS1 Antibody (L121/25)

Name: Anti-nNOS/NOS1 Antibody
Brand: NeuroMab
SKU: 75-480
Price: 337.0 USD
Availability: InStock

Our mouse nNOS/NOS1 monoclonal antibody from NeuroMab is produced in-house from clone L121/25. It detects human, mouse, and rat nNOS/NOS1 and is purified by Protein A chromatography. Works in WB, ICC, ELISA, AT.

Array tomography immunofluorescence volume reconstruction of 9 serial LRWhite-embedded 70 nm sections from adult mouse cortex layer 6 with L121/25 (green), rabbit Synapsin (Cell Signaling 5297, red). Image courtesy of Kristina Micheva (Stanford).

Array tomography immunofluorescence volume reconstruction of 9 serial LRWhite-embedded 70 nm sections from adult mouse cortex layer 6 with L121/25 (green), rabbit Synapsin (Cell Signaling 5297, red). Image courtesy of Kristina Micheva (Stanford).

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Species Reactivity

Human, Mouse, Rat

Applications

AT, ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-480

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

nNOS/NOS1

Scientific Background

Nitric Oxide Synthase 1 is encoded by the gene NOS1. NOS1 is a member of the NOS family. NOS1 synthesizes nitric oxide from L-arginine, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. NOS1 is expressed ubiquitously, with high levels of expression in skeletal muscle. Diseases associated with NOS1 include Achalasia, Familial Esophageal and Pyloric Stenosis, Infantile Hypertrophic, 1.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L121/25

Isotype

IgG2b

Applications

AT, ELISA, ICC, WB

Host Species

Mouse

Gene Name

NOS1

Molecular Weight

155-165 kDa for full-length protein, smaller fragments possible due to proteolysis and/or variable sample preparation

Immunogen

Fusion protein amino acids 350-720 of human NOS1 (accession number P29475) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2725813

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

NOS1 (Brain nitric oxide synthase) (Constitutive NOS) (Neuronal NOS) (Peptidyl-cysteine S-nitrosylase NOS1)

UniProt ID

P29475

Shipping

Shipped on ice packs

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Anti-nNOS/NOS1 Antibody (L121/25)

SKU: 75-480

Product Details

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