Anti-NGL-3/LRRC4B Antibody (N51/6)

Name: Anti-NGL-3/LRRC4B Antibody
Brand: NeuroMab
SKU: 75-085
Price: 337.0 USD
Availability: InStock

Our mouse NGL-3/LRRC4B monoclonal antibody from NeuroMab is produced in-house from clone N51/6. It detects mouse and rat NGL-3/LRRC4B and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with Myc-tagged NGL-1, NGL-2 NGL-3 or untagged Kv2.1 plasmid and probed with N51/6 (left) or K89/41 (right) TC supe.

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Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-085

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

NGL-3/LRRC4B

Scientific Background

Leucine Rich Repeat Containing 4B is encoded by the gene LRRC4B. LRRC4B is a synaptic adhesion protein that regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. LRRC4B is expressed in the brain. No disorders were found to be associated with LRRC4B.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N51/6

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Lrrc4b Lrig4

Molecular Weight

100 kDa

Immunogen

Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615) produced recombinantly in E. Coli

Immunogen Species

Rat

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2137617

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.15

Conjugate

Unconjugated

Specificity

No cross-reactivity against NGL-1 or NGL-2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)

UniProt ID

P0CC10

Shipping

Shipped on ice packs

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Anti-NGL-3/LRRC4B Antibody (N51/6)

SKU: 75-085

Product Details

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