Anti-Neuroligin-4 Antibody (N98/47)

Name: Anti-Neuroligin-4 Antibody
Brand: NeuroMab
SKU: 75-141
Price: 337.0 USD
Availability: InStock

Our mouse Neuroligin-4 monoclonal antibody from NeuroMab is produced in-house from clone N98/47. It detects mouse Neuroligin-4 and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult mouse brain membrane (MBM) and transfected cell immunoblot: extracts of MBM and COS cells transiently transfected with Neuroligin-1 and Neuroligin-4* plasmids and probed with N98/47. Data courtesy of Marc Bolliger and Tom Sudhof, UTSW (now at Stanford).

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Species Reactivity

Mouse

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-141

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Neuroligin-4

Scientific Background

Neuroligin4 is encoded by the gene NLGN4. Neuroligin4 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including retina and brain, where it is located at the postysynaptic membrane and is involved in regulation of synapses, synapse formation and synaptic transmission. Diseases associated with this gene include forms of Autism and Asperger Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N98/47

Isotype

IgG1

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

Nlgn4l Nl4* Nlgn4 Nlgn4x

Molecular Weight

125-130 kDa

Immunogen

Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin-4 (accession number ABS19580) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse

Antibody Registry ID

AB_11030369

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.67

Conjugate

Unconjugated

Specificity

Does not cross-react with other Neuroligins

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Neuroligin 4-like (Neuroligin-4) (NL-4)

UniProt ID

ABS19580

Shipping

Shipped on ice packs

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Anti-Neuroligin-4 Antibody (N98/47)

SKU: 75-141

Product Details

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