Anti-Myelin Basic Protein (MBP) Antibody

An antipeptide antibody was generated in chickens against a sequence shared between the mouse (NP_034907) and human (NP_002376) gene products. Antibodies were affinity-purified and the concentration adjusted to 100 µg/mL.

Immunohistochemical staining of MBP (RED) in the hippocampal region of a transgenic adult mouse brain. This particular transgenic mouse expresses low levels of GFP autofluorescence under control of an actin promoter region. The anti-MBP antibody (Aves Labs) was used at a 1:1000 dilution. Dr. Felix Eckenstein, University of Vermont.
Immunoblot images of MAG and MBP (Cat. MBP, 1:2000) in the somatosensory cortex of wildtype and GluD1 KO. Significant increase in MAG (***p PMID:37983226
Adult mouse cortical cultures were stained with chicken anti-MBP antibody (Aves Labs, green, 1:1000 dilution) and rabbit anti-GFAP antibody (EnCorBio, red; 1:1000 dilution). Photomicrograph courtesy of Dr. Gerry Shaw, Univ. Florida.
Immunohistochemical staining of the MBP (green) in the nodes of Ranvier of the sciatic nerve of an adult rat. Red counterstaining is a ubiquitous gene product. Blue shows DAPI nuclear staining. Photomicrograph courtesy of Dr. Gerry Shaw, Univ. Florida.
Immunostaining of MBP (red, 1:200), CD45(green, 1:100), and DAPI (1:1000, nuclei) of a mouse spinal cord lysophosphatidylcholine lesion. Image kindly provided by Charbel Baaklini, Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.
Immunostaining in the cortical and hippocampal region of paraffin embedded transgenic adult mouse brain identifying MBP (Cat. MBP, 1:1000, red) with nuclear staining with DAPI. Images taken with an epifluorescence microscope, 10x magnification. Image kindly provided by Begüm Kurt, Achucarro Basque Center for Neuroscience.
Immunohistochemical staining of the MBP (green) in the nodes of Ranvier of the sciatic nerve of an adult rat. Red counterstaining is a ubiquitous gene product. Blue shows DAPI nuclear staining. Photomicrograph courtesy of Dr. Gerry Shaw, Univ. Florida.
Chicken anti-Myelin Basic Protein (MBP) (green), with nuclei stained with Hoechst dye (blue).
Representative images passing through corpus callosum showing MBP (Cat. MBP 1:250; red) immunoreactivity in wildtype and GluD1 KO mice. A significant reduction in MBP staining was observed in GluD1 KO mice compared to wildtype following cuprizone treatmentImmunostaining in mouse corpus callosum in wild type and GluD1 knockouts labeling MBP. Image from publication CC-BY-4.0. PMID:37983226
MBP: frozen sections; all washes with Triton 0.5%; Region: Striatum; Blocking: BlockHen 1%; Secondary antibody: anti-chicken FITC (Aves); Epifluorescence microscope; 40x magnification.
Representative images are for myelin basic protein, MBP (Cat. MBP 1:250; red), staining in corpus callosum and motor cortex of wildtype and GluD1 KO mice at P40 and P180 and its quantification. GluD1 KO mice showed increased MBP staining in corpus callosum (*p = 0.0196, unpaired t-test) and motor cortex (****p PMID:37983226
Immunohistochemical staining of MBP (RED) in the hippocampal region of a transgenic adult mouse brain. This particular transgenic mouse expresses low levels of GFP autofluorescence under control of an actin promoter region. The anti-MBP antibody (Aves Labs) was used at a 1:1000 dilution. Dr. Felix Eckenstein, University of Vermont.
Immunohistochemical staining of MBP (RED) in the hippocampal region of a transgenic adult mouse brain. This particular transgenic mouse expresses low levels of GFP autofluorescence under control of an actin promoter region. The anti-MBP antibody (Aves Labs) was used at a 1:1000 dilution. Dr. Felix Eckenstein, University of Vermont.
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Human, Mouse, Rabbit, Rat, Sheep
ICC, IHC, WB
Chicken

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SKU: MBP

Volume: 1000 µL
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