Anti-Mitochondria Recombinant Chicken Chimeric mAb BTN Conjugate (113-1)

Name: Anti-Mitochondria Recombinant Chicken Chimeric mAb BTN Conjugate
Brand: Aves Labs
SKU: 78-607-BTN
Price: 562.0 USD
Availability: InStock

Our chicken Mitochondria biotin conjugate recombinant antibody from Aves Labs is produced in-house from clone 113-1. It detects human Mitochondria and is purified by affinity chromatography. Works in ELISA, ICC, IHC, WB.

Anti-Mitochondria Recombinant Chicken Chimeric mAb BTN Conjugate

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Species Reactivity

Human

Applications

ELISA, ICC, IHC, WB

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

Trial Size

SKU: 78-607-BTN

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Mitochondria

Scientific Background

Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

Format

Purified by affinity chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Recombinant

Clone

113-1

Isotype

IgY

Applications

ELISA, ICC, IHC, WB

Host Species

Chicken

Molecular Weight

60 kDa

Immunogen

Human cell homogenate

Immunogen Species

Human

Species Reactivity

Human

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone 113-1 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone 113-1 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

Biotin

Specificity

Specific for endogenous levels of the ~60 kDa human mitochondria. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

mitochondrial marker

Shipping

Shipped on ice packs

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Anti-Mitochondria Recombinant Chicken Chimeric mAb BTN Conjugate (113-1)

SKU: 78-607-BTN

Product Details

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