Our mouse L-Ficolin monoclonal antibody from Antibodies Incorporated is produced in-house from clone 19. It detects human L-Ficolin and is Protein A or Protein G purified. Works in ELISA, WB, IP.
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1).
Protein A or Protein G purified
1 mg/mL ±15%
Monoclonal
19
IgG2a/k
ELISA, WB
Mouse
FCN2
35 kDa
Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein.
Human
Human
2-8°C without exposure to light
Liquid
BSA free
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
ABS 005-19 is especially well suited as detecting antibody in a sandwich ELISA in combination with ABS 005-16. Furthermore, in ELISA, ABS 005-19 reacts with recombinant L-Ficolin coated directly into the microtiter well. (1)
Unconjugated
ABS 005-19 reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
