Anti-Kv6.1 Antibody (N474/27)

Name: Anti-Kv6.1 Antibody
Brand: NeuroMab
SKU: 75-490
Price: 337.0 USD
Availability: InStock

Our mouse Kv6.1 monoclonal antibody from NeuroMab is produced in-house from clone N474/27. It detects mouse Kv6.1 and is purified by Protein A chromatography. Works in ICC, ELISA.

Immunofluorescence of COS cells expressing Myc/Flag-tagged mouse Kv6.1/KCNG1. Green = N474/27, red = Rabbit anti-Myc and blue = Hoechst nuclear stain.

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Species Reactivity

Mouse

Applications

ELISA, ICC

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-490

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Kv6.1

Scientific Background

Potassium voltage-gated channel modifier subfamily G member 1 is encoded by the gene KCNG1. KCNG1 is a member of the potassium channel family, G (TC 1.A.1.2) subfamily, Kv6.1/KCNG1 sub-subfamily. KCNG1 is a potassium channel subunit that does not form functional channels by itself. It can form functional heterotetrameric channels with KCNB1. KCNG1 modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. KCNG1 is expressed in skeletal muscle. Diseases associated with KCNG1 include Colon Small Cell Carcinoma and Fragile X Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N474/27

Isotype

IgG1

Applications

ELISA, ICC

Host Species

Mouse

Gene Name

Kcng1

Molecular Weight

58 kDa

Immunogen

Fusion protein amino acids 1-227 (cytoplasmic N-terminus) of mouse Kv6.1 (accession number A2BDX4) produced recombinantly in E. Coli

Immunogen Species

Mouse

Species Reactivity

Mouse

Antibody Registry ID

AB_2744563

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Kv6.1 (Potassium voltage-gated channel subfamily G member 1) (Voltage-gated potassium channelsubunit Kv6.1)

UniProt ID

A2BDX4

Shipping

Shipped on ice packs

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Anti-Kv6.1 Antibody (N474/27)

SKU: 75-490

Product Details

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