Our mouse Kv1.4 K+ channel monoclonal antibody from NeuroMab is produced in-house from clone K13/31. It detects human, mouse, rabbit, and rat Kv1.4 K+ channel and is purified by Protein A chromatography. Works in WB, IHC, ICC, IP, ELISA.
Potassium voltage-gated channel subfamily A member 4 or Kv1.4 is encoded by the gene KCNA4. Kv1.4 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.4 is expressed in brain, and at lower levels in the testis, lung, kidney, colon, heart and adrenal tissue. In brain, Kv1.4 is located in the soma, dendrite and axon terminus of neurones in most regions of the brain.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
K13/31
IgG1
ELISA, ICC, IHC, IP, WB
Mouse
Kcna4
98 kDa
Synthetic peptide 13-37 of rat Kv1.4 (NSHMPYGYAAQARARERERLAHSR; accession number P15385)
Rat
Human, Mouse, Rabbit, Rat
AB_2249726
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
WB: 1:500
IHC: 1:250
ICC: 1:500
Unconjugated
No cross-reactivity against Kv1.1, Kv1.2, Kv1.3, Kv1.5 and Kv1.6 expressed in transfected cells
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Potassium voltage-gated channel subfamily A member 4 (RCK4) (RHK1) (RK3) (Voltage-gated potassium channel subunit Kv1.4)
![Immunoblot on membrane fractions of whole rat (RBM) and mouse (MBM) brain and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-010-k13-31-wb-2_120x120.jpg?v=1626902692)
