Anti-JMJD2A Antibody FL550 Conjugate (N154/32)

Name: Anti-JMJD2A Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-189-FL550
Price: 486.0 USD
Availability: InStock

Our mouse JMJD2A FL550 conjugate monoclonal antibody from NeuroMab is produced in-house from clone N154/32. It detects human JMJD2A and is purified by Protein A chromatography. Works in ICC.

Anti-JMJD2A Antibody FL550 Conjugate

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Species Reactivity

Human

Applications

ICC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-189-FL550

Volume: 200 µL

Variant

Price:

$486.00

Quantity:

Ships: 1-5 business days

Product Details

Target

JMJD2A

Scientific Background

Lysine Demethylase 4A is encoded by the gene KDM4A. KDM4A is a member of the JHDM3 histone demethylase family. KDM4A is a nuclear protein that contains a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. KDM4A is expressed is several organs with the highest expression in the lungs. Diseases associated with KDM4A include Attention Deficit-Hyperactivity Disorder.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

N154/32

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

KDM4A JHDM3A JMJD2 JMJD2A KIAA0677

Molecular Weight

120 kDa

Immunogen

Fusion protein amino acids 568-674 of human JMJD2A (accession number O75164) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_2939701

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with JMJD2C

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

Lysine-specific demethylase 4A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A)

UniProt ID

O75164

Shipping

Shipped on ice packs

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Anti-JMJD2A Antibody FL550 Conjugate (N154/32)

SKU: 75-189-FL550

Product Details

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