Anti-Haspin/GSG2 Antibody (N128A/2)

Name: Anti-Haspin/GSG2 Antibody
Brand: NeuroMab
SKU: 75-161
Price: 337.0 USD
Availability: InStock

Our mouse Haspin/GSG2 monoclonal antibody from NeuroMab is produced in-house from clone N128A/2. It detects human Haspin/GSG2 and is purified by Protein A chromatography. Works in WB, ICC, IP, ELISA.

Transfected cell immunofluorescence: COS cells expressing Myc-tagged human Haspin. Red = rabbit anti-Myc, Green = N128A/2, Blue = Hoechst nuclear stain.

Transfected cell immunoblot: extracts of COS cells transfected with Myc- tagged human Haspin and untagged Kv2.1 plasmids and probed with N128A/2 (left) and K89/41 (right) tissue culture supernatant.

Transfected cell immunofluorescence: COS cells expressing Myc-tagged human Haspin. Red = rabbit anti-Myc, Green = N128A/2, Blue = Hoechst nuclear stain.

Click on image to zoom

Species Reactivity

Human

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-161

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Haspin/GSG2

Scientific Background

Histone H3 Associated Protein Kinase is encoded by the gene HASPIN. HASPIN is a member of the protein kinase superfamily, Ser/Thr protein kinase family, and the Haspin subfamily. HASPIN is a serine/threonine - protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. HASPIN may act through H3T3ph to both position and modulate activation of AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment, and normal progression through the cell cycle. HASPIN is expressed in the testis, thymus, bone marrow, prostate, intestine, lung, spleen, and lymph node. No diseases were found to be associated with HASPIN.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N128A/2

Isotype

IgG1

Applications

ELISA, ICC, IP, WB

Host Species

Mouse

Gene Name

HASPIN GSG2

Molecular Weight

90 kDa

Immunogen

Fusion protein amino acids 1-798 (full-length) of human Haspin (accession number Q8TF76)

Immunogen Species

Human

Species Reactivity

Human

Antibody Registry ID

AB_2114890

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.87

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Serine/threonine-protein kinase haspin (EC 2.7.11.1) (Germ cell-specific gene 2 protein) (H-haspin) (Haploid germ cell-specific nuclear protein kinase)

UniProt ID

Q8TF76

Shipping

Shipped on ice packs

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Anti-Haspin/GSG2 Antibody (N128A/2)

SKU: 75-161

Product Details

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