Anti-GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) Antibody (49)

Name: Anti-GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) Antibody
Brand: Antibodies Incorporated
SKU: ABS 044-49-010
Price: 450.0 USD
Availability: InStock

Our mouse GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 49. It detects human GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) and is Protein A or Protein G purified. Works in ELISA, WB.

Anti-GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) Antibody

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Species Reactivity

Human

Applications

ELISA, WB

Host Species

Mouse

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Data Sheet

SKU: ABS 044-49-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GLP-1 (9-37) and GLP-1 (9-36) amide (N-term)

Scientific Background

Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

Isotype

IgG1/k

Applications

ELISA, WB

Host Species

Mouse

Gene Name

GCG

Molecular Weight

20 kDa (proglucagon)

Immunogen

Synthetic GLP-1(9-18)

Immunogen Species

Human

Species Reactivity

Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

ABS 044-49 binds free GLP-1(9-36)amide in solution. ABS 044-49 targets a different epitode than ABS 046-03B.

Conjugate

Unconjugated

Specificity

ABS 044-49 binds human GLP-1(9-36)amide. Based on inhibition ELISA, ABS 044-49 cross-reacts 3% with GLP-1(7-36)amide. The free N-terminus of GLP-1(9-36)amide and GLP-1(9-37).

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

UniProt ID

P01275

NCBI Gene ID

2641

Shipping

Shipped on ice packs

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Anti-GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) Antibody (49)

SKU: ABS 044-49-010

Product Details

Bulk Order Anti-GLP-1 (9-37) and GLP-1 (9-36) amide (N-term) Antibody

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