Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody Biotin Conjugate (10)

Name: Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody Biotin Conjugate
Brand: Antibodies Incorporated
SKU: ABS 033-10B-015
Price: 1929.0 USD
Availability: InStock

Our mouse GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) monoclonal biotinylated antibody from Antibodies Incorporated is produced in-house from clone 10. It detects human GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) and is Protein A or Protein G purified. Works in ELISA.

Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody Biotin Conjugate

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Species Reactivity

Human

Applications

ELISA

Host Species

Mouse

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Data Sheet

SKU: ABS 033-10B-015

Volume: 150 uL

Variant

Price:

$1,929.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GLP-1 (7-37) and GLP-1 (7-36) amide (N-term)

Scientific Background

Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

Isotype

IgG2a/k

Applications

ELISA

Host Species

Mouse

Gene Name

GCG

Molecular Weight

20 kDa (proglucagon)

Immunogen

Synthetic GLP-1(7-17)

Immunogen Species

Human

Species Reactivity

Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Application Details

ABS 033-10B can be used as a detection antibody in combination with ABS 046-03 as a capture antibody in order to measure non-amidated GLP-1 forms and cross-reacting about 5% with C-terminally amidated GLP-1.

Conjugate

Biotin

Specificity

ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

UniProt ID

P01275

NCBI Gene ID

2641

Shipping

Shipped on ice packs

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Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody Biotin Conjugate (10)

SKU: ABS 033-10B-015

Product Details

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