Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody (10)

Name: Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody
Brand: Antibodies Incorporated
SKU: ABS 033-10-010
Price: 450.0 USD
Availability: InStock

Our mouse GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) monoclonal antibody from Antibodies Incorporated is produced in-house from clone 10. It detects human GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) and is Protein A or Protein G purified. Works in ELISA, WB.

Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody

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Species Reactivity

Human

Applications

ELISA, WB

Host Species

Mouse

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Data Sheet

SKU: ABS 033-10-010

Volume: 100 uL

Variant

Price:

$450.00

Quantity:

Ships: 1-2 business days

Product Details

Target

GLP-1 (7-37) and GLP-1 (7-36) amide (N-term)

Scientific Background

Glucagon-like peptide 1(7-36)amide (GLP-1(7-36)amide) is the principal active form of GLP-1, the other being GLP-1(7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

Isotype

IgG2a/k

Applications

ELISA, WB

Host Species

Mouse

Gene Name

GCG

Molecular Weight

20 kDa (proglucagon)

Immunogen

Synthetic GLP-1(7-17)

Immunogen Species

Human

Species Reactivity

Human

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Application Details

ABS 033-10 binds free GLP-1(7-37) and free GLP-1(7-36)amide in solution. ABS 033-10 reacts in ELISA with GLP-1(7-37) coated directly onto the microtiter well. ABS 033-10 binds free exendin-4 in solution and can function as a capture antibody for exendin-4 in combination with ABS 012-35B in order to measure Exendin-4. ABS 046-03B as a biotinylated detection antibody and ABS 033-10 as a capture antibody can be used in sandwich ELISA.

Conjugate

Unconjugated

Specificity

ABS 033-10 binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(9-36)amide, glucagon and human GIP. Cross-reacts 0.25% with GLP-1(1-37), approximately 6% with human GLP-2 and approximately 50% with exendin-4. ABS 033-10 cross-reacts with Liraglutide.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

GCG, GLP-1, GLP1, GLP2, GRPP, pro-glucagon, glicentin-related polypeptide, glucagon-like peptide 1, glucagon-like peptide 2, incretin, preproglucagon

UniProt ID

P01275

NCBI Gene ID

2641

Shipping

Shipped on ice packs

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Anti-GLP-1 (7-37) and GLP-1 (7-36) amide (N-term) Antibody (10)

SKU: ABS 033-10-010

Product Details

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