Recombinant Mouse IL-18

Name: Recombinant Mouse IL-18
Brand: ImmunoChemistry Technologies
SKU: 6576
Price: 200.0 USD
Availability: InStock

Interleukin-18 (IL-18) is a proinflammatory cytokine that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection, and IL-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. Mouse IL-18 Recombinant Protein is purified interleukin-18 produced in yeast.

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SKU: 6576

Volume: 5 µg

Variant

Price:

$200.00

Quantity:

Ships: 1-2 business days

Product Details

Scientific Background

Interleukin-18 (IL-18) is a proinflammatory cytokine produced by macrophages and other cells that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS). After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-gamma (IFN-gamma) or type II interferon that plays an important role in activating macrophages or other cells. Apart from its physiological role, interleukin-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. This proinflammatory cytokine can induce the IFN-gamma production of T cells, and the combination of this cytokine and IL-12 has been shown to inhibit IL-4 dependent IgE and IgG1 production and to enhance IgG2a production of B cells.

Format

Lyophilized

Protein Sequence

NFGRLHCTTA VIRNINDQVL FVDKRQPVFE DMTDIDQSAS EPQTRLIIYM YKDSEVRGLA VTLSVKDSKM STLSCKNKII SFEEMDPPEN IDDIQSDLIF FQKRVPGHNK MEFESSLYEG HFLACQKEDD AFKLILKKKD ENGDKSVMFT LTNLHQS (157)

Source

Yeast

Contents

Recombinant proteins produced in yeast

Usage Statement

For research use only. Not for use in diagnostic procedures.

Country of Origin

United States

Storage

-20°C

Shipping

Ships at ambient temperature, Domestic: Overnight Delivery; International: Priority Shipping

The Mouse IL-18 protein can be used in cell culture, as an IL-18 ELISA Standard, and as a Western Blot Control.

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Recombinant Mouse IL-18

SKU: 6576

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