Products: Primary Antibodies

Anti-mGluR1/5 (Group I) glutamate receptor (N75/3)


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PRODUCT OPTIONS

Catalog # Option Volume Concentration Price*
Catalog #
75-115
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$205.00
Catalog #
73-115
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$180.00

Overview

Brand:

NeuroMab

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC IP WB

Immunogen:

Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b (also known as metabotropic glutamate receptor 5, accession number P31424)
Mouse: 96% identity (368/388 amino acids identical)
Human: 87% identity (339/388 amino acids identical)
<35% identity with mGluR1

Cross Reactivity:

Recognizes mGluR1 and mGluR5

Protein Name(s):

Metabotropic glutamate receptor 5 (mGluR5)

Gene Name(s):

Grm5 Gprc1e Mglur5

Antibody Registry ID:

Purified: AB_10672260
TC Supernatant: AB_10674107


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine/immunofluorescence staining pattern when used to stain brain sections.

Expected Banding Pattern:

130 kDa(both mGluR1 and mGluR5)


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.