ICC IHC WB
Glutamate receptor ionotropic, NMDA3A, N-Methyl-D-Aspartate Receptor Subtype 3A or GluN3A is encoded by the gene GRIN3A. GluN3A is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN3a is expressed in the CNS especially in development and appears to play a role in delaying synapse maturation. Diseases associated with GRIN3A include Macrodactyly
Fusion protein amino acids 58-87 or 152-176 (extracellular N-terminus) of mouse GluN3A (also known as Ionotropic glutamate receptor 3A, N-methyl-D-aspartate receptor subtype 3A, Glutamate receptor chi-1, NMDAR3A, NMDAR-L, NMDAR-L1, NR3A, Grin3A and KIAA1973, accession number A2AIR5)
Rat: 93% or 100% identity (28/30 or 25/25 amino acids identical)
Human: 83% or 96% identity (25/30 or 24/25 amino acids identical)
100% identity with Short isoform
50% identity with GluN3B/NR3B and other GluN/NMDA receptors
Glutamate receptor ionotropic, NMDA3A
TC Supernatant: AB_2491184
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.