Products: Primary Antibodies

Anti-Dardarin/LRRK2, C-terminus (N241A/34)


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PRODUCT OPTIONS

Catalog # Option Concentration Price*
Catalog #
75-253
Option
Purified
Concentration
1 mg/mL
Price
$219.00
Catalog #
73-253
Option
TC Supernatant
Concentration
Lot dependent
Price
$189.00

Overview

Brand:

NeuroMab

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC WB

Immunogen:

Fusion protein amino acids 970-2527 (C-terminus) of human LRRK2 (also known as Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin and PARK8, accession number Q5SS00)
Mouse: 89% identity (1393/1557 amino acids identical)
Rat:89% identity (1392/1557 amino acids identical) 30% identity with LRRK1This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.

Cross Reactivity:

None Reported

Protein Name(s):

Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)

Gene Name(s):

LRRK2 PARK8

Antibody Registry ID:

Purified: AB_10675136
TC Supernatant: AB_10671178


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Knockout Validation:

This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Expected Banding Pattern:

>200 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.