Human Mouse Rat
ICC IP WB
Calcium-activated potassium channel subunit beta-2, Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2 or BKbeta2 is encoded by the gene KCNMB2. BKbeta2 can bind to KCNMA1 to form a channel in the calcium activated large conductance (MaxiK channel) family. BKbeta2 acts to modulate the calcium sensitivity and gating kinetics of KCNMA1. BKbeta2 is expressed in the membrane in many tissues including kidney, heart, ovary and brain.
Fusion protein amino acids 1-41 (N-terminus) and 218-235 (C-terminus) of mouse BKBeta2 (accession number Q9CZM9); Human: 97% (N-terminus) and 100% (C-terminus) identity (40/41 and 18/18 amino acids identical); Mouse: 97% (N-terminus) and 100% (C-terminus) identity (40/41 and 18/18 amino acids identical)
No cross-reactivity against BKBeta1, BKBeta3 or BKBeta4
BKbeta2 K+ channel
TC Supernatant: AB_10674434
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.