Anti-TrpV1 Antibody (N221/17)

Name: Anti-TrpV1 Antibody
Brand: NeuroMab
SKU: 75-254
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

filler

Clonality

Monoclonal

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Trpv1 Vr1 Vr1l

Molecular Weight

100 kDa

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Immunofluorescence staining of adult dorsal root ganglion sections from TrpV1 WT and -/- mice with N221/17 TC supe (red), Kv1.2 rabbit polyclonal (green) and Hoechst nuclear stain (blue). Images courtesy of Matthew Rasband (Baylor College of Medicine).

Adult rat spinal cord dorsal horn immunohistochemistry.

Immunofluorescence staining of adult dorsal root ganglion sections from TrpV1 WT and -/- mice with N221/17 TC supe (red), Kv1.2 rabbit polyclonal (green) and Hoechst nuclear stain (blue). Images courtesy of Matthew Rasband (Baylor College of Medicine).

Product Details

Target

TrpV1

Target Description

Transient receptor potential cation channel subfamily V (vanilloid) member 1, or TrpV1 is a member of transient receptor potential cation channel family(TRP channel).TrpV1 is a non-selective, ligand activated calcium permeant cation channel that is widely expressed in tissues but elevated in dorsal root ganglia, highly but not solely expressed in postsynaptic dendritic spines. TrpV1 is involved in heat and chemical detection and in pain perception.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N221/17

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Trpv1 Vr1 Vr1l

Molecular Weight

100 kDa

Antigen

Fusion protein amino acids 1-160 (cytoplasmic N-terminus) of rat TrpV1 (also known as Transient receptor potential cation channel subfamily V member 1, Osm-9-like TRP channel 1, Vrl, accession number O35433); Mouse: 85% identity (137/161 amino acids identical); Human: 68% identity (110/161 amino acids identical) Less than 50% identity with TrpV4

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_11000725

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like)

UniProt Details

UniProt (Human): Q8NER1
UniProt (Immunogen Species): O35433

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Anti-TrpV1 Antibody (N221/17)

Anti-TrpV1 Antibody
SKU: 75-254

Product Details

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Anti-TrpV1 Antibody (N221/17)

Anti-TrpV1 Antibody SKU: 75-254

Product Details

Anti-TrpV1 Antibody
SKU: 75-254