MCG5959, isoform CRA_a (Potassium channel, subfamily K, member 16)
Potassium two pore domain channel subfamily K member 16 is encoded by the gene KCNK16. KCNK16 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK16 is an open rectifier which primarily passes outward current under physiological K+ concentrations. KCNK16 is expressed in the pancreas. Diseases associated with KCNK16 include Birk-Barel Syndrome and Maturity-Onset Diabetes of the Young.
Fusion protein amino acids 42-94 (first extracellular loop) and 259-292 (cytoplasmic C-terminus) of mouse TALK1 (also known as Potassium channel subfamily K member 16, 2P domain potassium channel Talk-1, TWIK-related alkaline pH-activated K(+) channel 1, Kcnk16, mCG_5959 and rCG_41914, accession number G5E845); Rat: 100% identity (53/53 amino acids identical) and 91% identity (31/34 amino acids identical); Human: 94% identity (50/53 amino acids identical) and 67% identity (24/36 amino acids identical); 50% identity with other potassium channel subunits
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.