Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Along with synaptotagmins 1 and 2, synaptotagmin 5 (also known as synaptotagmin 9) has been shown to function as a Ca(2+) sensor for fast synchronous neurotransmitter release (Xu J et al., 2007).
IHC, ICC, WB
Fusion protein amino acids 236-323 (cytoplasmic C2A domain) of mouse Synaptotagmin-5 (also known as Synaptotagmin-9, Synaptotagmin IX, SytIX, Syt9, Synaptotagmin-V, SytV and Syt5, accession number Q9R0N9); Rat: 100% identity (88/88 amino acids identical); Human: 98% identity (87/88 amino acids identical)50% identity with Synaptotagmin-10 (and other Synaptotagmins)
Syt nomenclature explanation: http://www.signaling-gateway.org/molecule/query?afcsid=A002563
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with Synaptotagmin-10 (or other Synaptotagmins)
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.