Anti-SVOP Antibody (N356/23)

Name: Anti-SVOP Antibody
Brand: NeuroMab
SKU: 75-353
Price: 319.0 USD
Availability: InStock

Our Anti-SVOP mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N356/23. It is KO validated, detects mouse and rat SVOP, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Immunoblot against adult rat brain membranes (RBM) and membranes from SVOP knockout (KO) and wild-type (WT) mice probed with N356/23 (left) and N52A/42 (right) TC supe. Mouse brains courtesy of Jia Yao and Sandra Bajjalieh (University of Washington.

Species Reactivity

Mouse, Rat

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

KO Validated

SKU: 75-353

Volume: 100 µL

Variant

Price:

$319

Quantity:

Product Details

Target

SVOP

Target Description

Synaptic vesicle 2-related protein or SVOP is encoded by the gene SVOP. SVOP contains 12 transmembrane regions and has transporter and ion transmembrane transporter activity. SVOP is expressed early in development and expressed in brain and endocrine cells where it is found in synaptic vesicles and microvesicles. Diseases associated with SVOP include Intestinal Botulism and Familial Atrial Fibrillation.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N356/23

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Svop

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 1-85 (MEEDLFQLRQLPVVKFRRTGESARSEDDAASGEHDVQIEGVRVGLEAVELDDGAAVPKEFANPTDDTFMVEDAVEAIGFGRFQWK, cytoplasmic N-terminus) of rat SVOP (accession number Q9Z2I7) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315934

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with SVOPL/SVOP2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Synaptic vesicle 2-related protein (SV2-related protein)

UniProt Details

UniProt (Human): Q8N4V2
UniProt (Immunogen Species): Q9Z2I7

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Anti-SVOP Antibody (N356/23)

SKU: 75-353

Product Details

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