Anti-Slo2.1/Slick K+ Channel Antibody (N11/33)

Name: Anti-Slo2.1/Slick K+ Channel Antibody
Brand: NeuroMab
SKU: 75-055
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

filler

Clonality

Monoclonal

Applications

IHC, WB

Host Species

Mouse

Gene Name

Kcnt2

Molecular Weight

140 kDa

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Immunoblot against brain membranes from adult rat (RBM) or from Slo2.1 knockout (MBM-Slo2.1 KO) or wild-type (MBM-WT) mice probed with N11/33 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).

Adult rat hippocampal immunohistochemistry.

Adult rat whole brain immunohistochemistry.

Immunoblot against brain membranes from adult rat (RBM) or from Slo2.1 knockout (MBM-Slo2.1 KO) or wild-type (MBM-WT) mice probed with N11/33 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).

Product Details

Target

Slo2.1/Slick K+ channel

Target Description

Potassium sodium-activated channel subfamily T member 2 is encoded by the gene KCNT2. KCNT2 is a member of the potassium channel family, calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily. KCNT2 is an outward rectifying potassium channel which produces rapidly activating outward rectifying K+ currents. KCNT2 is expressed in the brain and skin. Diseases associated with KCNT2 include Early Infantile Epileptic Encephalopathy 57 and Bulbar Polio.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N11/33

Isotype

IgG1

Applications

IHC, WB

Host Species

Mouse

Gene Name

Kcnt2

Molecular Weight

140 kDa

Antigen

Fusion protein amino acids 564-624 of mouse Slo2.1 (Slick; XP_920840); Human: 91% identity (64/70 amino acids identical); Rat: 98% identity (69/70 amino acids identical)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2296599

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Potassium channel, subfamily T, member 2

UniProt Details

UniProt (Human): Q6UVM3
UniProt (Immunogen Species): D3Z649

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Anti-Slo2.1/Slick K+ Channel Antibody (N11/33)

Anti-Slo2.1/Slick K+ Channel Antibody
SKU: 75-055

Product Details

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Anti-Slo2.1/Slick K+ Channel Antibody (N11/33)

Anti-Slo2.1/Slick K+ Channel Antibody SKU: 75-055

Product Details

Anti-Slo2.1/Slick K+ Channel Antibody
SKU: 75-055