Immunoblot against brain membranes from adult rat (RBM) or from Slo2.1 knockout (MBM-Slo2.1 KO) or wild-type (MBM-WT) mice probed with N11/33 (left) or N52A/42 (right) TC supe. Mouse brains courtesy of Chris Lingle (Washington University).
Anti-Slo2.1/Slick K+ Channel Antibody
Slo2.1/Slick K+ channel
Potassium sodium-activated channel subfamily T member 2 is encoded by the gene KCNT2. KCNT2 is a member of the potassium channel family, calcium-activated (TC 1.A.1.3) subfamily, KCa4.2/KCNT2 sub-subfamily. KCNT2 is an outward rectifying potassium channel which produces rapidly activating outward rectifying K+ currents. KCNT2 is expressed in the brain and skin. Diseases associated with KCNT2 include Early Infantile Epileptic Encephalopathy 57 and Bulbar Polio.