Anti-SCG10/Stathmin-2 Antibody (L5/1)

Name: Anti-SCG10/Stathmin-2 Antibody
Brand: NeuroMab
SKU: 75-063
Price: 337.0 USD
Availability: InStock

Our mouse SCG10/Stathmin-2 monoclonal antibody from NeuroMab is produced in-house from clone L5/1. It detects human, mouse, and rat SCG10/Stathmin-2 and is purified by Protein A chromatography. Works in WB, IHC, ICC, IP, ELISA.

Cultured hippocampal neurons (9 DIV) double- Stained for MAP2 (red), L5/1 (green).

Adult rat neocortex immunohistochemistry.

Adult rat hippocampus immunohistochemistry.

Cultured hippocampal neurons (9 DIV) double- Stained for MAP2 (red), L5/1 (green).

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-063

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

SCG10/Stathmin-2

Scientific Background

Stathmin 2, Superior Cervical Ganglia, Neural Specific 10 (SCG10) is encoded by the gene STMN2 and is a member of the stathmin family of phosphoproteins. Stathmin 2 is involved in regulation of microtubule dynamics and signal transduction. In this manner, Stathmin 2 plays a regulatory role in neuronal growth. Stathmin 2 is expressed in brain in neurons and present in growth cones developing neurons. Diseases associated with STMN2 include down syndrome and Creutzfeldt-jakob disease.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L5/1

Isotype

IgG2b

Applications

ELISA, ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

Stmn2 Scg10 Scgn10

Molecular Weight

˜20 kDa L5/1 does not work for immunoblotting

Immunogen

Synthetic peptide 155-179 C-terminus of rat SCG10 (ERLQEKERHAAEVRRNKELQVELSG; accession number P21818)

Immunogen Species

Rat

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2302747

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4

Dilution Ranges

WB: 1:250
ICC: 1:500

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Scg10; Stathmin-2; Superior cervical ganglion-10 protein; stathmin-like 2; Protein SCG10; superiorcervical ganglia; neural specific 10

UniProt ID

P21818
UniProt Summary: Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.

NCBI Gene ID

84510

Shipping

Shipped on ice packs

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Anti-SCG10/Stathmin-2 Antibody (L5/1)

SKU: 75-063

Product Details

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