QKI5 is a member of the Signal Transduction and Activation of RNA proteins (STAR proteins) family. QKI5, QKI6 QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. QKI5 is a RNA-binding protein. QKI5 has roles in the regulation of splicing, export and stability of mRNA. It is involved in myelinization. It is a nuclear isoform and contains a C-terminal nuclear localization signal. Diseases associated with this gene include Angiocentric Glioma, 6Q Terminal Deletion Syndrome .and Schizophrenia.
IHC, ICC, WB
Qki Qk QKI HKQ Qk1 Qka1
40 kDa (and others)
Synthetic peptide amino acids 315-331 (ATKVRRHDMRVHPYQRI, with nuclear localization signal underlined) of human QKI-5 (also known as Protein quaking, HqkI and Hqk, accession number Q96PU); Mouse: 100% identity (17/17 amino acids identical); Rat: 100% identity (17/17 amino acids identical) No identity with QKI-6, QKI-7 and QKI-7b
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with QKI-6, QKI-7 or QKI-7bCross-reacts with other STAR proteins containing similar nuclear localization signals
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.