Anti-NrCAM Antibody (N343/26)

Name: Anti-NrCAM Antibody
Brand: NeuroMab
SKU: 75-325
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N343/26

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

Nrcam Kiaa0343

Molecular Weight

160 kDa

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Immunofluorescence staining of a node of Ranvier in adult rat sciatic nerve with N343/26 (green) and bIV-spectrin rabbit polyclonal (red). Image courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine.

Volume: 100 µL

Variant

Price:

$295

Quantity:

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Product Details

Target

Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (mBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)

Target Description

Neuronal Cell Adhesion Molecule is encoded by the gene NRCAM. NRCAM is a member of the immunoglobulin superfamily, L1/neurofascin/NgCAM family. NRCAM is an ankyrin-binding protein that is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM also may play a role in cell-cell communication via signalling from its intracellular domain to the actin cytoskeleton during directional cell migration. NRCAM is expressed in the brain. Diseases associated with NRCAM include Masa Syndrome and Autism.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N343/26

Isotype

IgG2a

Applications

ICC, WB

Host Species

Mouse

Gene Name

Nrcam Kiaa0343

Molecular Weight

160 kDa

Antigen

Fusion protein amino acids 30-845 (extracellular domain) of mouse NrCAM (also known as Neuronal cell adhesion molecule, Ankyrin-binding cell adhesion molecule, Neuronal surface protein Bravo, NgCAM-related cell adhesion molecule and KIAA0343, accession number Q810U4) Rat: 96% identity (795/822 amino acids identical) Human: 91% identity (753/822 amino acids identical) ~50% identity with Neurofascin

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315900

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Neuronal cell adhesion molecule (Nr-CAM) (Neuronal surface protein Bravo) (mBravo) (NgCAM-related cell adhesion molecule) (Ng-CAM-related)

UniProt Details

UniProt (Human): Q92823
UniProt (Immunogen Species): Q810U4

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Anti-NrCAM Antibody (N343/26)

Anti-NrCAM Antibody
SKU: 75-325

Bulk Order Anti-NrCAM Antibody

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