Neuroligin2 is encoded by the gene NLGN2. Neuroligin2 is a transmembrane scaffolding protein and cell adhesion molecule. It is involved in cell-cell interactions in neurons and in other cell types. It is expressed in many tissues, including the brain where it is located at the postysynaptic membrane and is involved in regulation of inhibitory synapses, synapse formation and synaptic transmission. Diseases associated with this gene include Pervasive Developmental Disorder and Autism.
ICC, IHC, WB
Fusion protein amino acids 700-836 (cytoplasmic C-terminus) of mouse Neuroligin-2 (also known as Nlgn2 and Kiaa1366, accession number Q69ZK9); Rat: 100% identity (137/137 amino acids identical); Human: 99% identity (136/137 amino acids identical); 40% identity with Neuroligin-3 and other Neuroligin proteins
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