Mitochondrial Rho GTPase 2 (Miro2) or Ras Homolog Family Member T2 is encoded by the gene RHOT2 and is a member of the Rho family of GTPases. Miro2 is a mitochondrial GTPase. It is found on the outer mitochondrial membrane and is involved in mitochondrial trafficking. Miro2 is ubiquitously expressed in tissues. Diseases associated with this gene include 3-Methylglutaconic Aciduria and, Autosomal Recessive Congenital Hypomyelinating Neuropathy.
Purified by Protein A chromatography
ICC, IHC, WB
RHOT2 ARHT2 C16orf39
Fusion protein amino acids 343-580 (second Miro domain) of human Miro2 (accession number Q8IXI1) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Does not cross-react with Miro1
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)