Anti-GluN3A/NR3A Antibody (N416/40)

Name: Anti-GluN3A/NR3A Antibody
Brand: NeuroMab
SKU: 75-416
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N416/40

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Grin3a

Molecular Weight

110 kDa

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Immunofluorescence staining of unpermerabilized COS cells transiently transfected with GFP- tagged GluN3A/NR3a and GluN1/NR1 plasmids with N416/40 (red). Images courtesy of Sonia Marco Martinez and Isabel Perez- Otano (University of Navarra).

Immunoblot against crude membranes from neonatal or adult rat brain (RBM) and extracts of COS cells transiently transfected with untagged GluN3A/NR3A or Kv2.1 plasmid probed with N416/40 (left) or K35/40 (right) TC supe.

Immunofluorescence staining of permeabilized.

Immunofluorescence staining of unpermerabilized COS cells transiently transfected with GFP- tagged GluN3A/NR3a and GluN1/NR1 plasmids with N416/40 (red). Images courtesy of Sonia Marco Martinez and Isabel Perez- Otano (University of Navarra).

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

Glutamate receptor ionotropic, NMDA3A

Target Description

Glutamate receptor ionotropic, NMDA3A, N-Methyl-D-Aspartate Receptor Subtype 3A or GluN3A is encoded by the gene GRIN3A. GluN3A is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN3a is expressed in the CNS especially in development and appears to play a role in delaying synapse maturation. Diseases associated with GRIN3A include Macrodactyly

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N416/40

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Grin3a

Molecular Weight

110 kDa

Antigen

Fusion protein amino acids 58-87 or 152-176 (extracellular N-terminus) of mouse GluN3A (also known as Ionotropic glutamate receptor 3A, N-methyl-D-aspartate receptor subtype 3A, Glutamate receptor chi-1, NMDAR3A, NMDAR-L, NMDAR-L1, NR3A, Grin3A and KIAA1973, accession number A2AIR5); Rat: 93% or 100% identity (28/30 or 25/25 amino acids identical); Human: 83% or 96% identity (25/30 or 24/25 amino acids identical); 100% identity with Short isoform; 50% identity with GluN3B/NR3B and other GluN/NMDA receptors

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2532049

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Glutamate receptor ionotropic, NMDA3A

UniProt Details

UniProt (Human): Q8TCU5
UniProt (Immunogen Species): A2AIR5

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Anti-GluN3A/NR3A Antibody (N416/40)

Anti-GluN3A/NR3A Antibody
SKU: 75-416

Bulk Order Anti-GluN3A/NR3A Antibody

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Anti-GluN3A/NR3A Antibody (N416/40)

Anti-GluN3A/NR3A Antibody SKU: 75-416

Bulk Order Anti-GluN3A/NR3A Antibody

Product Details

Anti-GluN3A/NR3A Antibody
SKU: 75-416