Immunofluorescence staining of unpermerabilized COS cells transiently transfected with GFP- tagged GluN3A/NR3a and GluN1/NR1 plasmids with N416/40 (red). Images courtesy of Sonia Marco Martinez and Isabel Perez- Otano (University of Navarra).
Glutamate receptor ionotropic, NMDA3A
Glutamate receptor ionotropic, NMDA3A, N-Methyl-D-Aspartate Receptor Subtype 3A or GluN3A is encoded by the gene GRIN3A. GluN3A is a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of channel forming ionotropic glutamate receptor which is permeable to cations including calcium, potassium and sodium. GluN3a is expressed in the CNS especially in development and appears to play a role in delaying synapse maturation. Diseases associated with GRIN3A include Macrodactyly
ICC, IHC, WB
Fusion protein amino acids 58-87 or 152-176 (extracellular N-terminus) of mouse GluN3A (also known as Ionotropic glutamate receptor 3A, N-methyl-D-aspartate receptor subtype 3A, Glutamate receptor chi-1, NMDAR3A, NMDAR-L, NMDAR-L1, NR3A, Grin3A and KIAA1973, accession number A2AIR5); Rat: 93% or 100% identity (28/30 or 25/25 amino acids identical); Human: 83% or 96% identity (25/30 or 24/25 amino acids identical); 100% identity with Short isoform; 50% identity with GluN3B/NR3B and other GluN/NMDA receptors
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.