Anti-GIT2 Antibody (N83/48)

Name: Anti-GIT2 Antibody
Brand: NeuroMab
SKU: 75-126
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N83/48

Applications

IHC, IP, WB

Host Species

Mouse

Format

Purified

Gene Name

GIT2 KIAA0148

Molecular Weight

85 kDa

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Transfected cell immunoblot: extracts of rat brain membranes (RBM) and COS cells transiently transfected with Flag-tagged GIT1 and GIT2 and untagged Kv2.1 plasmids and probed with N83/48 (left) and K89/41 (right) TC supe and with anti-Flag antibody (middle).

Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

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Product Details

Target

GIT2

Target Description

G-protein coupled receptor kinase interacting ArfGAP 2 is encoded by the gene GIT2. GIT2 is a member of the GIT protein family. GIT2 has a be shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 is expressed in 207 organs with the highest expression level in the right hemisphere of cerebellum. Diseases associated with GIT2 include Gastric Antral Vascular Ectasia and Systemic Scleroderma.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N83/48

Isotype

IgG1

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

GIT2 KIAA0148

Molecular Weight

85 kDa

Antigen

Fusion protein amino acids 450-759 (C-terminus) of human GIT2 (also known as ARF GTPaseactivating protein, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2,Cool-interacting tyrosine-phosphorylated protein 2 and CAT2, accession number Q14161); Mouse: 88% identity (263/298 amino acids identical); Less than 50% identity with GIT1

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2110013

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity against GIT1

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)

UniProt Details

UniProt (Human): Q14161
UniProt (Immunogen Species): Q14161

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Anti-GIT2 Antibody (N83/48)

Anti-GIT2 Antibody
SKU: 75-126

Bulk Order Anti-GIT2 Antibody

Product Details

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Anti-GIT2 Antibody (N83/48)

Anti-GIT2 Antibody SKU: 75-126

Bulk Order Anti-GIT2 Antibody

Product Details

Anti-GIT2 Antibody
SKU: 75-126