Anti-Gamma-Protocadherin-C3 Antibody (N174B/27)

Name: Anti-Gamma-Protocadherin-C3 Antibody
Brand: NeuroMab
SKU: 75-237
Price: 329.0 USD
Availability: InStock

1 Citation

Our Anti-Gamma-protocadherin-C3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N174B/27. It detects mouse Gamma-protocadherin-C3, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged Gamma- protocadherin-C3 and –A3 and untagged Kv2.1 plasmids and probed with N174B/27 (left) and N159/5 (right) TC supe.

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Species Reactivity

Mouse

Applications

ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-237

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Gamma-protocadherin-C3

Target Description

Protocadherin Gamma Subfamily C, 3 is encoded by the gene PCDHGC3. PCDHGC3 is a member of the protocadherin gamma gene cluster. PCDHGC3 is a neural cadherin-like cell adhesion protein that most likely plays a critical role in the establishment and function of specific cell-cell connections in the brain. PCDHGC3 is expressed in the nervous system, liver, and skin. Diseases associated with PCDHGC3 include Corneal Dystrophy, Endothelial, X-Linked and Brachydactyly, Type A3.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N174B/27

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Pcdhgc3

Molecular Weight

100 kDa

Antigen

Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-C3 (accession number Q91XX1) produced recombinantly in E. Coli

Species Reactivity

Mouse

Antibody Registry ID

AB_10672245

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity against other Gamma-protocadherin-A, -B or -C proteins

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Protocadherin gamma C3 (Protocadherin gamma subfamily C, 3)

UniProt ID

Q91XX1

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
31877124	1:500-1:1000	Garrett, A.M., et al. 2019. CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4. . PLoS genetics, e1008554.

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Anti-Gamma-Protocadherin-C3 Antibody (N174B/27)

SKU: 75-237

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-Gamma-Protocadherin-C3 Antibody

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