Anti-GABA-A-R, Beta3 Antibody (N87/25)

Our Anti-GABA(A)R, Beta3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N87/25. It detects human and mouse GABA(A)R, Beta3, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.



SKU: 75-149

Volume: 100 µL
1-2 business days
Price:
Sale price$319

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
232362761:250Fuks, J.M., et al. 2012. GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii.. PLoS Pathogens, e1003051.
Immunocytochemistry: Mouse
PMID Dilution Publication
369976091:300Giansante, G., et al. 2023. Neuronal Network Activity and Connectivity are Impaired in a Conditional Knockout Mouse Model with PCDH19 Mosaic Expression. Molecular Psychiatry, .
349368761:1000Garcia, J.D., et al. 2021. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Reports, 110142.
318351701:500Niwa, F., et al. 2019. cAMP-EPAC-Dependent Regulation of Gephyrin Phosphorylation and GABAAR Trapping at Inhibitory Synapses. iScience, 453-465.
316656291:200Moretto, E., et al. 2019. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Reports, 1130-1146.e8.
31315046not listedNathanson, A.J., et al. 2019. Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures. Cell Reports, 670-681.
306673601:5 (supe)Andrews, N.P., et al. 2019. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain. Elife, e43322.
236726801:250Alicea, B., et al. 2013. Defining the diversity of phenotypic respecification using multiple cell lines and reprogramming regimens.. Stem Cells and Development, 2641-2654.
217350591:500Yanovsky, Y., et al. 2012. GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.. Pflügers Archiv: European Journal of Physiology, 187-199.
Immunocytochemistry: Rat
PMID Dilution Publication
340470071:500Yang, X., et al. 2021. Differential regulation of glycinergic and GABAergic nanocolumns at mixed inhibitory synapses. EMBO Reports, e52154.
316656291:200Moretto, E., et al. 2019. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Reports, 1130-1146.e8.
282626621:300Zapata, J., et al. 2017. Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission. Nature Communications, 14536.
229279411:500, et al. 2012. Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes.. PLoS One, e42959.
204172811:100 (supe)Smith, K.R., et al. 2010. Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons.. Molecular and Cellular Neuroscience, 330-341.
Immunohistochemistry: Mouse
PMID Dilution Publication
261791221:1000He, Q., et al. 2015. Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells.. Nature Communications, 7364.
223516361:1000Sumegi, M., et al. 2012. Virus-mediated swapping of zolpidem-insensitive with zolpidem-sensitive GABA(A) receptors in cortical pyramidal cells.. The Journal of Physiology, 1517-1534.
214828241:500Jo, Y.H., et al. 2011. Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse.. The Journal of Biological Chemistry, 19993-20004.
Immunohistochemistry: Rat
PMID Dilution Publication
275371971:1000Kerti-Szigeti, K., et al. 2016. Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells. Elife, e18426.
244779621:5 (supe)King, A.N., et al. 2014. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. . Journal of Comparative Neurology, 2594-2608.
225398471:2000, et al. 2012. Setting the time course of inhibitory synaptic currents by mixing multiple GABA(A) receptor α subunit isoforms.. Journal of Neuroscience, 5853-5867.
220986311:800Kerti, K., et al. 2012. Unique somato-dendritic distribution pattern of Kv4.2 channels on hippocampal CA1 pyramidal cells.. European Journal of Neuroscience, 66-75.
19815531not listedArancibia-Cárcamo, I.L., et al. 2009. Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition.. PNAS: USA, 17552-17557.
Immunoprecipitation: Rat
PMID Dilution Publication
240894942ugPribiag, H., et al. 2014. TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors.. Journal of Neuroscience, 15879-15893.
Western Blot: Human
PMID Dilution Publication
223030154ug/mlGurba, K.N., et al. 2012. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating.. The Journal of Biological Chemistry, 12083.
Western Blot: Mouse
PMID Dilution Publication
349368761:5000Garcia, J.D., et al. 2021. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Reports, 110142.
33147470not listedRudolph, S., et al. 2020. ArticleCerebellum-Specific Deletion of the GABAAReceptordSubunit Leads to Sex-Specific Disruptionof Behavior. Cell Reports, 108338.
30791981not listedFu, Y.L., et al. 2019. LMAN1 (ERGIC-53) promotes trafficking of neuroreceptors. Biochemical and Biophysical Research Communications, 356-362.
281541401 : 500Sterky, F.H., et al. 2017. Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.. PNAS: USA, E1253-E1262.
270447421:1000Nakamura, Y., et al. 2016. Proteomic Characterization of Inhibitory Synapses Using a Novel pHluorin-tagged γ-Aminobutyric Acid Receptor, Type A (GABAA), α2 Subunit Knock-in Mouse. Journal of Biological Chemistry, 12394-12407.
24153177not listedHan, K., et al. 2014. SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.. Nature, 72-77.
237440691:100Zhou, C., et al. 2013. Altered cortical GABAA receptor composition, physiology, and endocytosis in a mouse model of a human genetic absence epilepsy syndrome.. The Journal of Biological Chemistry, 21458-21472.
Western Blot: Rat
PMID Dilution Publication
325799171:1000Rajgor, D., et al. 2020. Local miRNA-dependent translational control of GABAAR synthesis during inhibitory long-term potentiation. Cell reports, 31(12), p.107785.. Cell reports, 107785.
25310985not listedPiguel, N.H., et al. 2014. Scribble1/AP2 complex coordinates NMDA receptor endocytic recycling. Cell Reports, 712-727.
240894941:500Pribiag, H., et al. 2014. TNF-α downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors.. Journal of Neuroscience, 15879-15893.
204172811:10 (supe)Smith, K.R., et al. 2010. Identification and characterisation of a Maf1/Macoco protein complex that interacts with GABAA receptors in neurons.. Molecular and Cellular Neuroscience, 330-341.
Additional Publications: Unspecified
PMID Publication
26732589Mele, M., et al. 2017. Downregulation of GABAA Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia.. Molecular Neurobiology, 45-57.
25510230Babateen, O., et al. 2015. Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma.. European Journal of Pharmacology, 101-107.
25402556Marty, V.N., et al. 2015. Radiation-induced alterations in synaptic neurotransmission of dentate granule cells depend on the dose and species of charged particles.. Radiation Research, 653-665.
24513087Mele, M., et al. 2014. GABA(A) receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia.. Neurobiology of Disease, 220-232.
20980909Fagerlund, M.J., et al. 2010. The human carotid body: expression of oxygen sensing and signaling genes of relevance for anesthesia.. Anesthesiology, 1270-1279.
20470805Adusei, D.C., et al. 2010. Early developmental alterations in GABAergic protein expression in fragile X knockout mice.. Neuropharmacology, 167-171.

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