Our Anti-Brevican mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N294A/10. It is KO validated, detects mouse and rat Brevican, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Immunofluorescence staining of adult spinal cord sections from Brevican wild-type (WT) and knockout (KO) mice with N294A/10 (red) and Caspr rabbit polyclonal (green). Images courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine).
Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.
Purified by Protein A chromatography
Fusion protein amino acids 219-655 of rat Brevican (accession number P55068) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)