Anti-Brevican Antibody (N294A/10)

Name: Anti-Brevican Antibody
Brand: NeuroMab
SKU: 75-294
Price: 319.0 USD
Availability: InStock

Our Anti-Brevican mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N294A/10. It is KO validated, detects mouse and rat Brevican, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Immunofluorescence staining of adult spinal cord sections from Brevican wild-type (WT) and knockout (KO) mice with N294A/10 (red) and Caspr rabbit polyclonal (green). Images courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine).

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

490

550

594

650

Go to Full Product Details

Data Sheet

KO Validated

SKU: 75-294

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Brevican

Target Description

Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N294A/10

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Bcan Behab

Molecular Weight

140 kDa

Antigen

Fusion protein amino acids 219-655 of rat Brevican (accession number P55068) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315824

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)

UniProt Details

UniProt (Human): Q96GW7
UniProt (Immunogen Species): P55068

Product Specific References for Applications and Species

Immunohistochemistry: Mouse

Immunohistochemistry: Mouse
PMID	Dilution	Publication
34180393	1:500	Stevens, S.R., et al. 2021. Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3. 1b K+ channels. . Elife, e66491.
31571216	1:200	Collins, L.N., et al. 2020. The mouse olfactory peduncle 4: Development of synapses, perineuronal nets, and capillaries. Journal of Comparative Neurology, 637-649.

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Anti-Brevican Antibody (N294A/10)

SKU: 75-294

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-Brevican Antibody

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