Immunofluorescence staining of adult spinal cord sections from Brevican wild-type (WT) and knockout (KO) mice with N294A/10 (red) and Caspr rabbit polyclonal (green). Images courtesy of Kae-Jiun Chang and Matt Rasband (Baylor College of Medicine).
Bulk Order Anti-Brevican Antibody
Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)
Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.
Fusion protein amino acids 219-655 of rat Brevican (also known as Brevican core protein, Brain-enriched hyaluronan-binding protein, BEHAB, BCAN, Chondroitin sulfate proteoglycan 7 and CSPG7, accession number P55068); Mouse: 92% identity (403/437 amino acids identical); Human: 75% identity (350/464 amino acids identical); 40% identity with Aggrecan
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.