Tissue and transfected cell immunoblot: extracts of rat eye and brain membrane (REM and RBM, respectively) and COS cells transiently transfected with Myc-tagged BBS5 or untagged Kv2.1 plasmid and probed with N304B/115 (left) and N52A/42 (right) TC supe.
Bardet-Biedl syndrome 5 protein
Bardet-Biedl syndrome 5 protein or BBS5 is encoded by the gene BBS5 and is one component of the BBSome, a complex of proteins that regulates the protein composition in cilia. The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. BBS5 is expressed in many tissues including brain, heart, eye, kidney and testes. Diseases associated with BBS5 include Bardet-Biedl Syndrome 5and Bardet-Biedl Syndrome.
Fusion protein amino acids 150-273 of human BBS5 (also known as Bardet-Biedl syndrome 5 protein and rCG_26204, accession number Q8N3I7)
Rat: 99% identity (123/124 amino acids identical)
Mouse: 99% identity (123/124 amino acids identical)
Less than 50% identity with other BBS proteins
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.