Anti-nNOS/NOS1 Antibody Biotin Conjugate (L121/42)

Name: Anti-nNOS/NOS1 Antibody Biotin Conjugate
Brand: NeuroMab
SKU: 75-481-BTN
Price: 543.0 USD
Availability: InStock

Our mouse nNOS/NOS1 biotin conjugate monoclonal antibody from NeuroMab is produced in-house from clone L121/42. It detects human, mouse, and rat nNOS/NOS1 and is purified by Protein A chromatography. Works in ELISA, IHC, ICC, WB.

Anti-nNOS/NOS1 Antibody Biotin Conjugate

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Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-481-BTN

Volume: 200 µL

Variant

Price:

$543.00

Quantity:

Ships: 1-5 business days

Product Details

Target

nNOS/NOS1

Scientific Background

Nitric Oxide Synthase 1 is encoded by the gene NOS1. NOS1 is a member of the NOS family. NOS1 synthesizes nitric oxide from L-arginine, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. NOS1 is expressed ubiquitously, with high levels of expression in skeletal muscle. Diseases associated with NOS1 include Achalasia, Familial Esophageal and Pyloric Stenosis, Infantile Hypertrophic, 1.

Format

Purified by Protein A chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Monoclonal

Clone

L121/42

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

NOS1

Molecular Weight

155-165 kDa for full-length protein, smaller fragments possible due to proteolysis and/or variable sample preparation

Immunogen

Fusion Protein Amino acids 350-720 of human NOS1 (accession number P29475) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

Biotin

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

IHPS1; NOS1; NC-NOS; Brain nitric oxide synthase; bNOS; Constitutive NOS; nNOS; Neuronal NOS; nitric oxide synthase; Peptidyl-cysteine S-nitrosylase NOS1; brain; NOS type I; nitric oxide synthase 1 (neuronal; NOS

UniProt ID

P29475
UniProt Summary: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.

NCBI Gene ID

4842

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Anti-nNOS/NOS1 Antibody Biotin Conjugate (L121/42)

SKU: 75-481-BTN

Product Details

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