Fluo-3, AM Ester, 1 mM in anhydrous DMSO Fluorescent Calcium Indicator

Name: Fluo-3, AM Ester, 1 mM in anhydrous DMSO Fluorescent Calcium Indicator
Brand: Antibodies Incorporated
SKU: 81-3005
Price: 319.0 USD
Availability: InStock

Our Fluo-3, AM Ester is a non-ratiometric calcium indicator that increases in fluorescence intensity upon calcium binding. Calcium imaging is widely used to measure neuronal activity.

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Applications

EM, ICC, IHC

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Data Sheet

SKU: 81-3005

Volume: 1 mL

Variant

Price:

$319.00

Quantity:

Ships: 1-5 business days

Product Details

Scientific Background

To study the roles of calcium, a key intracellular messenger in cells, it is essential to quantitatively monitor its concentration. The most widely used method of Ca2+ detection is the use of fluorescent Ca2+ indicators. Fluo-3, AM ester is a membrane-permeant form of Fluo-3 that can be loaded into cells via incubation. Fluo-3 AM ester itself does not bind Ca2+, but it is readily hydrolyzed to Fluo-3 by endogenous esterases once the dye is inside the cells. An important application of Fluo-3 AM ester is its use in high throughput drug screening.

Concentration

1 mM

Applications

EM, ICC, IHC

Molecular Weight

1129.9 Da

Excitation / Emission

Kd: 450 nM, Ex: 506 nm, Em: 526 nm

Storage

Store at –20°C, protect from light.

Physical State

Solid

Specificity

Membrane-permeant, non-ratiometric; can be loaded into cells via incubation.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

Stable for 12 months after date of receipt.

Shipping

Shipped at ambient temperature; protected from light

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Fluo-3, AM Ester, 1 mM in anhydrous DMSO Fluorescent Calcium Indicator

SKU: 81-3005

Product Details

Bulk Order Fluo-3, AM Ester, 1 mM in anhydrous DMSO Fluorescent Calcium Indicator

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