ICC IHC WB
Trafficking kinesin-binding protein 1 or O-Linked N-Acetylglucosamine Transferase Interacting Protein 106 is encoded by the gene TRAK1. TRAK1 is involved in mitochondrial motility and regulation of endosome-to-lysosome trafficking. TRAK1 can bind both kinesin and dynein. TRAK1 is ubiquitously expressed in tissues. Diseases associated with this gene include Early Infantile Epileptic Encephalopathy and Undetermined Early-Onset Epileptic Encephalopathy.
Fusion protein amino acids 1-110 (N-terminus) of human TRAK1 (also known as Trafficking kinesinbinding protein 1, 106 kDa O-GlcNAc transferase-interacting protein, Ensembl ENSRNOP00000026106, KIAA1042, OIP106 and rCG_25699, accession number Q9UPV9)
Rat: 89% identity (98/110 amino acids identical)
Mouse: 88% identity (97/110 amino acids identical)
<50% identity with TRAK2
Does not cross-react with TRAK2
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein)
TRAK1 KIAA1042 OIP106
TC Supernatant: AB_2315945
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.