Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (also known as Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin and Stg, accession number Q71RJ2)
Mouse: 100% identity (121/121 amino acids identical)
Human: 96% identity (117/121 amino acids identical) >50% identity with TARPGamma3, TARPGamma4 and TARPGamma8
Does not cross-react with TARPGamma3, TARPGamma4 and TARPGamma8
Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Stargazin) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2)
TC Supernatant: AB_10675452
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Rademacher N1, Schmerl B1, Lardong JA2, Wahl MC2, Shoichet SA1.. (2016), 'MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density..' Sci Rep.. 10.1038/srep35283.
- Pandey SP1, Rai R, Gaur P, Prasad S.. (2015), 'Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain..' Biogerontology.. 10.1007/s10522-014-9548-6.
- Maheshwari A1, Nahm WK, Noebels JL.. (2013), 'Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice..' Front Cell Neurosci. . 10.3389/fncel.2013.00156.
- Tao Y1, Chen YJ, Shen C, Luo Z, Bates CR, Lee D, Marchetto S, Gao TM, Borg JP, Xiong WC, Mei L.. (2013), 'Erbin interacts with TARP γ-2 for surface expression of AMPA receptors in cortical interneurons..' Nat Neurosci.. 10.1038/nn.3320.