Products: Primary Antibodies

Anti-TARPGamma2/Stargazin Antibody (N245/1)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-242
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-242
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2a

Species Reactivity:

Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC WB

Target Description:

Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.

Immunogen:

Fusion protein amino acids 203-323 (cytoplasmic C-terminus) of rat TARPGamma2 (also known as Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin and Stg, accession number Q71RJ2); Mouse: 100% identity (121/121 amino acids identical); Human: 96% identity (117/121 amino acids identical)
Greater than 50% identity with TARPGamma3, TARPGamma4 and TARPGamma8

Cross Reactivity:

Does not cross-react with TARPGamma3, TARPGamma4 and TARPGamma8

Protein Name(s):

TARPGamma2/Stargazin

Gene Name(s):

Cacng2 Stg

Antibody Registry ID:

Purified: AB_11001587
TC Supernatant: AB_10675452


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Knockout Validation:

This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).

Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

36 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.