Human Mouse Rat
Fusion protein amino acids 1-183 (cytoplasmic N-terminus) of mouse SynDIG1 (also known as Synapse differentiation-inducing gene protein 1, Dispanin subfamily C member 2, Transmembrane protein 90B, DSPC2, Tmem90b and C20orf39, accession number A2ANU3)
Rat: 97% identity (179/183 amino acids identical)
Human: 91% identity (167/183 amino acids identical)
50% identity with SynDIG1L/SynDIG2/Capucin/Tmem90a
Synapse differentiation-inducing gene protein 1 (SynDIG1) (Dispanin subfamily C member 2) (DSPC2) (Transmembrane protein 90B)
TC Supernatant: AB_11000166
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
- Kirk LM1, Ti SW2, Bishop HI2, Orozco-Llamas M1, Pham M1, Trimmer JS2,3, Díaz E1.. (2016), 'Distribution of the SynDIG4/proline-rich transmembrane protein 1 in rat brain..' J Comp Neurol.. 10.1002/cne.23945.
- Sumioka A1, Brown TE, Kato AS, Bredt DS, Kauer JA, Tomita S.. (2011), 'PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity..' Nat Neurosci.. 10.1038/nn.2952.
- Kalashnikova E1, Lorca RA, Kaur I, Barisone GA, Li B, Ishimaru T, Trimmer JS, Mohapatra DP, Díaz E.. (2010), 'SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development..' Neuron.. 10.1016/j.neuron.2009.12.021.