Products: Primary Antibodies
PRODUCT OPTIONS
Brand | Catalog # | Option | Volume | Concentration | Price | |
---|---|---|---|---|---|---|
Brand![]() |
Catalog # 75-177 |
Option Purified |
Volume 100 µL |
Concentration 1 mg/mL |
Price $285.00 |
|
Brand![]() |
Catalog # 73-177 |
Option TC Supernatant |
Volume 5 mL |
Concentration Lot dependent |
Price $285.00 |
Product Details
Monoclonal
Mouse
IgG1
Mouse
ICC WB
Protocadherin gamma A3 is encoded by the gene Pcdhga3. Gamma-protocadherins belong to a superfamily of homophilic cell-adhesion proteins. These cell adhesion proteins are thought to be involved in establishing and function of cell-cell connections in brain. Gamma-Protocadherin-A3 is a type I transmembrane receptor and is a calcium-dependent cell-adhesion protein. Gamma-Protocadherin-A3 plays a role in the establishment and maintenance of specific neuronal connections in the brain. Gamma-Protocadherin-A3 is expressed in the central nervous system where it localizes to synapses. Diseases associated with this gene include Pineal Gland Cancer.
Fusion protein amino acids 720-804 (variable cytoplasmic domain) of mouse Gamma-protocadherin-A3 (also known as PCDH-gamma-A3, accession number Q91XY5); Human: 80% identity (68/84 amino acids identical); Greater than 75% identity with other Gamma-protocadherin-A proteins
No cross-reactivity against other Gamma-protocadherin-A, -B or -C proteins
Gamma-protocadherin-A3
Pcdhga3
Purified: AB_10671815
TC Supernatant: AB_10697874
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody has been knockout-validated in mouse brain (by Western blot and/or immunohistochemistry).
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
100 kDa
Quality Control
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.