Zinedin, Stiatin4 or Protein Phosphatase 2 Regulatory Subunit B'Gamma is encoded by the gene STRN4 and is a member of the Striatin family (which also includes Stiatin and SG2NA). Zinedin is a scaffolding protein with multiple protein binding domains. Zinedin binds calmodulin and acts as a calcium dependent signaling protein. Zinedin is found in the brain and the nervous system. Diseases associated with this gene includeing Cerebral Cavernous Malformations 3 and Muscular Dystrophy-Dystroglycanopathy.
IHC, IP, WB
Fusion protein amino acids 42-354 of human Zinedin/Striatin-4 (accession number Q9NRL3); Rat: 95% identity (300/313 amino acids identical); Mouse: 96% identity (300/313 amino acids identical); 52% identity with human Striatin-3
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