Zinedin, Stiatin4 or Protein Phosphatase 2 Regulatory Subunit B'Gamma is encoded by the gene STRN4 and is a member of the Striatin family (which also includes Stiatin and SG2NA). Zinedin is a scaffolding protein with multiple protein binding domains. Zinedin binds calmodulin and acts as a calcium dependent signaling protein. Zinedin is found in the brain and the nervous system. Diseases associated with this gene includeing Cerebral Cavernous Malformations 3 and Muscular Dystrophy-Dystroglycanopathy.
Purified
1 mg/mL
Monoclonal
K88/64
IgG2a
IHC, IP, WB
Mouse
STRN4 ZIN
95 kDa
Fusion protein amino acids 42-354 of human Zinedin/Striatin-4 (accession number Q9NRL3); Rat: 95% identity (300/313 amino acids identical); Mouse: 96% identity (300/313 amino acids identical); 52% identity with human Striatin-3
Rat
AB_2197913
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.