Anti-Zinedin Antibody (K88/64)

Name: Anti-Zinedin Antibody
Brand: NeuroMab
SKU: 75-099
Price: 319.0 USD
Availability: InStock

Our Anti-Zinedin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K88/64. It detects rat Zinedin, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Adult rat hippocampus immunohistochemistry.

Immunoblot on adult rat brain membranes.

Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)]..

Immunoblot on adult rat brain membranes in comparison with commercial anti-Striatin antibody.

Adult rat hippocampus immunohistochemistry.

Species Reactivity

Rat

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

Go to Full Product Details

Data Sheet

SKU: 75-099

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Zinedin

Target Description

Zinedin, Stiatin4 or Protein Phosphatase 2 Regulatory Subunit B'Gamma is encoded by the gene STRN4 and is a member of the Striatin family (which also includes Stiatin and SG2NA). Zinedin is a scaffolding protein with multiple protein binding domains. Zinedin binds calmodulin and acts as a calcium dependent signaling protein. Zinedin is found in the brain and the nervous system. Diseases associated with this gene includeing Cerebral Cavernous Malformations 3 and Muscular Dystrophy-Dystroglycanopathy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K88/64

Isotype

IgG2a

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

STRN4 ZIN

Molecular Weight

95 kDa

Antigen

Fusion protein amino acids 42-354 of human Zinedin/Striatin-4 (accession number Q9NRL3) produced recombinantly in E. Coli

Species Reactivity

Rat

Antibody Registry ID

AB_2197913

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.26

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Striatin-4 (Zinedin)

UniProt Details

UniProt (Human): Q9NRL3
UniProt (Immunogen Species): Q9NRL3

Product Specific References for Applications and Species

Immunocytochemistry: Rat
Immunoprecipitation: Rat
Western Blot: Rat

Immunocytochemistry: Rat
PMID	Dilution	Publication
27537937	1:100	Juraszek, B., et al. 2016. Protein phosphatase PP2A - a novel interacting partner of carnitine transporter OCTN2 (SLC22A5) in rat astrocytes.. Journal of Neurochemistry, 537-551.
23015759	not listed	Chen, Y.K., et al. 2012. CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex.. Molecular Biology of the Cell, 4383-4392.
18466332	not listed	Benoist, M., et al. 2008. Distribution of zinedin in the rat brain.. Journal of Neurochemistry, 969-977.

Immunoprecipitation: Rat
PMID	Dilution	Publication
27537937	not listed	Juraszek, B., et al. 2016. Protein phosphatase PP2A - a novel interacting partner of carnitine transporter OCTN2 (SLC22A5) in rat astrocytes.. Journal of Neurochemistry, 537-551.

Western Blot: Rat
PMID	Dilution	Publication
27537937	1:1000	Juraszek, B., et al. 2016. Protein phosphatase PP2A - a novel interacting partner of carnitine transporter OCTN2 (SLC22A5) in rat astrocytes.. Journal of Neurochemistry, 537-551.
23015759	not listed	Chen, Y.K., et al. 2012. CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex.. Molecular Biology of the Cell, 4383-4392.
18466332	not listed	Benoist, M., et al. 2008. Distribution of zinedin in the rat brain.. Journal of Neurochemistry, 969-977.

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Anti-Zinedin Antibody (K88/64)

SKU: 75-099

Product Details

Product Specific References for Applications and Species

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