Synaptotagmins are a family of calcium sensing, membrane trafficking proteins. 17 different synaptotagmins have been identified in mammals. Along with synaptotagmins 1 and 2, synaptotagmin 9 (also known as synaptotagmin 5) has been shown to function as a Ca(2+) sensor for fast synchronous neurotransmitter release (Xu J et al., 2007).
ICC, IHC, WB
Fusion protein amino acids 253-344 (cytoplasmic C2B domain) of mouse Synaptotagmin-9 (also known as Synaptotagmin-5, Synaptotagmin V, SytV, Syt5, Synaptotagmin-IX, SytIX and Syt9, accession number Q9R0N5); Rat: 100% identity (92/92 amino acids identical); Human: 100% identity (92/92 amino acids identical)Greater than 50% identity with Synaptotagmin-1 (and other Synaptotagmins)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with Synaptotagmin-1 (or other Synaptotagmins)
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.