Anti-SUR2A Antibody (N319A/14)

Name: Anti-SUR2A Antibody
Brand: NeuroMab
SKU: 75-296
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

1 Citation

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N319A/14

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Abcc9 Sur2

Molecular Weight

120 kDa

Go to Full Product Details

Immunoblot versus extracts of heart tissue from WT and SUR2 KO mice probed with N319A/14 TC supe. Data courtesy of William Coetzee and Margaret Rice, New York University SOM.

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

Target Description

Sulfonylurea receptor 2A (SUR2A), or ATP binding cassette transporter subfamily C member 9 is encoded by the gene ABCC9 and is a member of the ABC transporter super family. Differential splicing of the ABCC9 gene produces 2 isoforms, SUR2A and SUR2B. SUR2A forms cardiac and smooth muscle-type KATP channels with KCNJ11(Kir6.2) and is involved in regulation and activation. Diseases associated with this gene include Cantu Syndrome and Dilated Cardiomyopathy 1O.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N319A/14

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Abcc9 Sur2

Molecular Weight

120 kDa

Antigen

Fusion protein amino acids 1505-1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A (also known as Sulfonylurea receptor 2A, ATP-binding cassette transporter sub-family C member 9A and Abcc9A, accession number P70170); Rat: 97% identity (41/42 amino acids identical); Human: 92% identity (39/42 amino acids identical); 100% identity with SUR2CLess than 50% identity with SUR2B

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315928

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with SUR2B

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

UniProt Details

UniProt (Human): O60706
UniProt (Immunogen Species): P70170

Hong M1, Bao L, Kefaloyianni E, Agullo-Pascual E, Chkourko H, Foster M, Taskin E, Zhandre M, Reid DA, Rothenberg E, Delmar M, Coetzee WA. (2012), 'Heterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated disk..' J Biol Chem. 10.1074/jbc.M112.412122.

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Anti-SUR2A Antibody (N319A/14)

Anti-SUR2A Antibody
SKU: 75-296

Bulk Order Anti-SUR2A Antibody

Product Details

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Anti-SUR2A Antibody (N319A/14)

Anti-SUR2A Antibody SKU: 75-296

Bulk Order Anti-SUR2A Antibody

Product Details

Anti-SUR2A Antibody
SKU: 75-296